ARTICLES :

PubMed : In Vivo Anti-Cancer Mechanism of Low-Molecular-Weight Fucosylated Chondroitin Sulfate (LFCS) from Sea Cucumber Cucumaria frondosa.

PubMed : Transport and uptake effects of marine complex lipid liposomes in small intestinal epithelial cell models.

PubMed : Structure of Sphingolipids From Sea Cucumber Cucumaria frondosa and Structure-Specific Cytotoxicity Against Human HepG2 Cells.

PubMed : Fucoidan from sea cucumber Cucumaria frondosa exhibits anti-hyperglycemic effects in insulin resistant mice via activating the PI3K/PKB pathway and GLUT4.

PubMed : The WNT/β-catenin pathway is involved in the anti-adipogenic activity of cerebrosides from the sea cucumber Cucumaria frondosa.

PubMed : Novel Use of PIT Tags in Sea Cucumbers: Promising Results with the Commercial Species Cucumaria frondosa.

PubMed : Sea Cucumbers Metabolites as Potent Anti-Cancer Agents.

PubMed : Cytotoxic and apoptosis-inducing activity of triterpene glycosides from Holothuria scabra and Cucumaria frondosa against HepG2 cells.

PubMed : Frondoside A enhances the antiproliferative effects of gemcitabine in pancreatic cancer.

PubMed : The protective effect of eicosapentaenoic acid-enriched phospholipids from sea cucumber Cucumaria frondosa on oxidative stress in PC12 cells and SAMP8 mice.

PubMed : Eicosapentaenoic acid-enriched phosphatidylcholine isolated from Cucumaria frondosa exhibits anti-hyperglycemic effects via activating phosphoinositide 3-kinase/protein kinase B signal pathway.

PubMed : Isolation of cytotoxic glucoerebrosides and long-chain bases from sea cucumber Cucumaria frondosa using high speed counter-current chromatography.

PubMed : Frondoside a suppressive effects on lung cancer survival, tumor growth, angiogenesis, invasion, and metastasis.

PubMed : Analysis and comparison of glucocerebroside species from three edible sea cucumbers using liquid chromatography-ion trap-time-of-flight mass spectrometry.

PubMed : Frondoside A inhibits breast cancer metastasis and antagonizes prostaglandin E receptors EP4 and EP2.

PubMed : Frondoside A inhibits human breast cancer cell survival, migration, invasion and the growth of breast tumor xenografts.

PubMed : A novel stiffening factor inducing the stiffest state of holothurian catch connective tissue.

PubMed : Anti-pancreatic cancer effects of a polar extract from the edible sea cucumber, Cucumaria frondosa.

PubMed : Chemopreventive effects of Frondanol A5, a Cucumaria frondosa extract, against rat colon carcinogenesis and inhibition of human colon cancer cell growth.

PubMed : [Complexation between triterpene glycosides of holothurians and cholesterol is the basis of lipid-saponin carriers of subunit protein antigens].

PubMed : Review of the apoptosis pathways in pancreatic cancer and the anti-apoptotic effects of the novel sea cucumber compound, Frondoside A.

PubMed : Immunomodulatory properties of frondoside A, a major triterpene glycoside from the North Atlantic commercially harvested sea cucumber Cucumaria frondosa. 

PubMed : [Characteristics of proteinase digestive function in invertebrates–inhabitants of cold seas].

PubMed : Exogonadal oogenesis in a temperate holothurian.

PubMed : Compositional characteristics and antioxidant properties of fresh and processed sea cucumber (Cucumaria frondosa).

PubMed : Tensilin-like stiffening protein from Holothuria leucospilota does not induce the stiffest state of catch connective tissue. 

PubMed : Interactions among contaminants and nutritional lipids during mobilization by digestive fluids of marine invertebrates.

PubMed : Purification, characterization and cloning of tensilin, the collagen-fibril binding and tissue-stiffening factor from Cucumaria frondosa dermis.

PubMed : Antibacterial activity in Strongylocentrotus droebachiensis (Echinoidea), Cucumaria frondosa (Holothuroidea), and Asterias rubens (Asteroidea).

PubMed : The detection and isolation of a novel antimicrobial peptide from the echinoderm, Cucumaria frondosa. 

PubMed : Intermediate filament proteins in echinoderm coelomocytes. 

PubMed : Dynamic mechanical characterization of a mutable collagenous tissue: response of sea cucumber dermis to cell lysis and dermal extracts. 

PubMed : Collagen fibril aggregation-inhibitor from sea cucumber dermis. 

PubMed : Cell-derived stiffening and plasticizing factors in sea cucumber (Cucumaria frondosa) dermis

PubMed : [Biomedical research on a concentrate of carotenoids made from the North Atlantic sea cucumber Cucumaria frondosa]. 

PubMed : A triterpenoid saponin from Cucumaria frondosa.

PubMed : Growth of sea cucumber collagen fibrils occurs at the tips and centers in a coordinated manner. 

PubMed : Partial biochemical and immunologic characterization of fibrillin microfibrils from sea cucumber dermis. 

PubMed : Stiparin: a glycoprotein from sea cucumber dermis that aggregates collagen fibrils. 

PubMed : Morphology and biomechanics of the microfibrillar network of sea cucumber dermis 

PubMed : Novel sulfated oligosaccharides from the sea cucumber Cucumaria frondosa.

PubMed : Coelomocyte aggregation in Cucumaria frondosa: effect of ethylenediaminetetraacetate, adenosine, and adenosine nucleotides.

THE IDEAL SUPPLEMENT FOR BETTER HEALTH

Sea Cucumber is the most amazing superfood, backed by human history, legend and scientific research throughout the world, but the Cucumaria frondosa species is truly a gift from the sea

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